Rapid jump on psa12/31/2023 However, some men who have prostate cancer do not exhibit elevated PSA levels. This can lead to overproduction of PSA, and higher levels of PSA in the bloodstream. Prostate cancer causes cells to become malignant and multiply uncontrollably. The cancer’s stage is further determined based on two additional factors: the PSA level and the Gleason scale. This staging system is based on the size or extent of the tumor, the number of lymph nodes involved, and whether or not the cancer has spread or metastasized to distant sites or organs. Prostate cancer, like many other cancers, is described based on the American Joint Committee on Cancer‘s TMN (tumor, metastasis, node) staging system. Stages range from 1 to 4, with higher numbers indicating more advanced disease. Organizing prostate cancer into stages is done to communicate how far along the disease is, and to help plan treatment. This may interfere with prostate cancer screening and the accuracy of a PSA level test.Ī 2010 study found nonsteroidal anti-inflammatory drugs (such as Aleve and Advil), statins (drugs that lower cholesterol) and thiazide diuretics (which treat high blood pressure) had a statistically significant impact on PSA levels when taken long term.įinasteride and dutasteride, medications commonly used to treat male-pattern hair loss and enlarged prostate, also cause reduction in PSA levels. A 2020 study found 34.6 percent of prostate cancer patients experienced UTIs.Ĭertain medications can actually lower PSA as a side effect. They can occur alongside other health issues in the prostate. Most urinary tract infections are caused by bacteria. In general, a higher PSA level indicates a higher chance of prostate cancer. ![]() In rare instances, prostate cancer can spread elsewhere in the body. The gland swells, and isn’t able to function properly. This occurs when malignant cells grow uncontrollably in the prostate’s tissues. Also called prostate enlargement, this condition can cause frequent and strained urination, and increased urination at night, among other symptoms. This refers to inflammation and swelling in the gland and surrounding areas, often due to bacterial infection. Several health factors and conditions related to the prostate can cause the gland to produce more PSA than normal.
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